Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
TRPM7 Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 5.2E-16 0.531 0.731
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731
TAS2R62P taste 2 receptor member 62 pseudogene 0.729 0.192
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC30A6 Q6NXT4 solute carrier family 30 member 6 Transporter 6.9E-09 0.711 0.346
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
RELN P78509 reelin 1.00 0.515 0.731
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
PTK2B Q14289 protein tyrosine kinase 2 beta Kinase 0.94 0.448 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846